Brochure
Ostinol® Advanced - Product Brochure
Gain quick access to product information, insights, and patient benefits of Ostinol® Advanced.
Download NowOstinol® Advanced - 5X and 5X Max Joint Products Brochure
Gain quick access to product information, insights, and patient benefits of Ostinol® Advanced 5x Products
DOWNLOAD NOWWebinar/Podcasts
THE BREAKTHROUGH IN REGENERATIVE HEALTH AND MEDICINE: NEW MODALITIES IN BONE AND JOINT HEALTH
October 29th, 2025
In this webinar, Dr. Greenberg explores the latest breakthroughs in regenerative health and medicine, including Prolotherapy, PRP, and Stem Cell Therapy. Discover how these cutting-edge treatments are transforming bone, joint, and women’s health, and learn the role of Bone Morphogenetic Proteins (BMPs).
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MAST CELL ACTIVATION, COVID-19, AND OSTEOPOROSIS: THE BMP CONNECTION
September 10th, 2025
In this webinar, Dr. Cynthia Worden highlights new research and understandings of how bone morphogenetic proteins (BMPs) play a critical role in the link between mast cell activation, post-Covid-19 complications, and osteoposoris.
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POST-MENOPAUSAL WOMEN AND OSTEOPOROSIS: THE BMP CONNECTION
May 8th, 2025
In this webinar, Dr. Patterson highlights new research and explores how Bone Morphogenetic Proteins (BMPs) play a critical role in the link between post-menopausal women and conditions such as osteoporosis, osteoarthritis, and Lyme disease.
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MAST CELL ACTIVATION, COVID-19, AND OSTEOPOROSIS: THE BMP CONNECTION
April 17th, 2025
In this webinar, Dr. Cynthia Worden highlights new research and understandings of how bone morphogenetic proteins (BMPs) play a critical role in the link between mast cell activation, post-Covid-19 complications, and osteoposoris.
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INFLAMMATION IN MUSCULOSKELETAL CONDITIONS & A NOVEL GROWTH-FACTOR COMPLEX
March 20th, 2025
In this webinar, the father and son chiropractic team of Drs. Frank and Matthew Cucolo explore the mechanism and impact of inflammation, and introduce Cyplexinol® - Nature’s BMP-Complex for musculoskeletal regenerative nutrition.
Watch NowRegenerative Health and Medicine - a Deep Dive into BMP
This episode of the OneMedicine Podcast features an in-depth discussion on the new frontiers of regenerative health and medicine, with a deep dive into BMP (bone morphogenetic protein) complexes.
Clinical Studies
Dietary Supplementation With Cyplexinol® For Amelioration of Osteoporosis
By: Keith Wilkinson, ND; Paul Howard, MD, MACP, FACR
Download NowThe Dietary Supplement Cyplexinol® Alleviates Joint Pain in Men and Women
By: Jacquelyn Pence, Michelle Stockton, Richard J. Bloomer
Download NowCyplexinol® — an oral growth-factor complex shows promise for knee and hip: Clinical trial insights
By: Richard Garian, DC, CCSP; James J. Scaffidi, BS
DOWNLOAD NOWBreakthroughs in arthritis – the BMP connection
By: Richard Garian, DC, MS; Arlene Donar, ND; Donald DeFabio, DC; Nancy Gahles, DC; James J. Scaffidi, BS
Download NowClinical Rounds and New Frontiers
Clinical Rounds Overview
Regenerative Tissue Science, LLC. is proud to present this educational mini-series on stem cell activation with natural bone and cartilage stimulating proteins, reshaping and bridging allopathic and natural medicine.
download nowClinical Rounds - Part 1
Bone and Cartilage Stimulating Protein Complex: Supports de novo Bone and Cartilage Tissue Regeneration via Stem Cell Activation.
DOWNLOAD NOWClinical Rounds – Part 2
Clinical Uses of Oral Bone and Cartilage Stimulating Protein Complex: Meeting the Unmet Medical Need in Bone and Cartilage Management.
DOWNLOAD NOWClinical Rounds - Part 3
New paradigm for addressing joint health through bone and cartilage stimulation.
DOWNLOAD NOWClinical Rounds - Part 4
New paradigm for addressing joint health through bone and cartilage stimulation.
DOWNLOAD NOWClinical Rounds - Part 5
Enhanced Immune Responses - Properties of Bone and Cartilage Stimulating Protein Complex
DOWNLOAD NOWRegenerative Support for the Jaw: Introducing Ostinol® powered by Cyplexinol® for Holistic Dentistry
Supporting Jaw Bone Health with Natural Growth Factor Science
DOWNLOAD NOWScientific and Medical Papers Research on BMPs and BMPs Complexes — not on Cyplexinol® or Ostinol® products
Scientific and Medical Papers Research on BMPs and BMPs Complexes
Reduced Expression of BMP-4 and BMP-5 in Arthritis Synovium
“Expression of bone morphogenetic proteins BMP-4 and BMP-5 in synovial tissue from patients with osteoarthritis and rheumatoid arthritis”
learn moreSerum BMPs in Rheumatoid Arthritis (BMP-2, BMP-4, BMP-7)
“Evaluation of serum levels of BMP-2, BMP-4 and BMP-7 in patients with rheumatoid arthritis”
LEARN MOREBMP-9 Promotes Bone Formation in Arthritis Models
“BMP-9 promotes osteogenesis in rheumatoid arthritis synovium via the Smad1/5/8 signaling pathway”
Learn MoreBMP-7 Intra-articular Injections Improve Cartilage in OA
“Intra-articular administration of bone morphogenetic protein-7 retards progression of cartilage degeneration in rabbit experimental osteoarthritis”
Learn MoreDynamic BMP Signaling in Experimental Arthritis
“Dynamic changes in BMP signaling during the development of experimentally induced arthritis”
Learn MoreBMP-2 Inhibits Pro-Inflammatory Cytokine IL-34 in RA Synoviocytes
“BMP-2 and TGF-β1 down-regulate IL-34 expression in fibroblast-like synoviocytes of patients with rheumatoid arthritis”
Learn MoreBMP-7 and HO-1 Linked to Bone Markers in RA/AS
“Elevated expression of bone morphogenetic protein 7 (BMP-7) and heme oxygenase-1 (HO-1) in patients with rheumatoid arthritis and ankylosing spondylitis”
Learn MorePhase I Trial: BMP-7 in Knee Osteoarthritis
“Safety and tolerability of intra-articular recombinant human bone morphogenetic protein-7 in moderate to severe knee osteoarthritis”
Learn MorePatient Education Series
EDUCATION PARTNERS
For more resources and information on regenerative health and medicine, visit our education partner.