Podcasts

Regenerative Health and Medicine - a Deep Dive into BMP

This episode of the OneMedicine Podcast features an in-depth discussion on the new frontiers of regenerative health and medicine, with a deep dive into BMP (bone morphogenetic protein) complexes.

Webinars

INFLAMMATION IN MUSCULOSKELETAL CONDITIONS & A NOVEL GROWTH-FACTOR COMPLEX

In this webinar, the father and son chiropractic team of Drs. Frank and Matthew Cucolo explore the mechanism and impact of inflammation, and introduce Cyplexinol® - Nature’s BMP-Complex for musculoskeletal regenerative nutrition.

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MAST CELL ACTIVATION, COVID-19, AND OSTEOPOROSIS: THE BMP CONNECTION

In this webinar, Dr. Cynthia Worden highlights new research and understandings of how bone morphogenetic proteins (BMPs) play a critical role in the link between mast cell activation, post-Covid-19 complications, and osteoposoris.

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POST-MENOPAUSAL WOMEN AND OSTEOPOROSIS: THE BMP CONNECTION

In this webinar, Dr. Patterson highlights new research and explores how Bone Morphogenetic Proteins (BMPs) play a critical role in the link between post-menopausal women and conditions such as osteoporosis, osteoarthritis, and Lyme disease.

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Case Studies

Dietary Supplementation With Cyplexinol® For Amelioration of Osteoporosis

By: Keith Wilkinson, ND; Paul Howard, MD, MACP, FACR

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The Dietary Supplement Cyplexinol® Alleviates Joint Pain in Men and Women

By: Jacquelyn Pence, Michelle Stockton, Richard J. Bloomer

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Cyplexinol® — an oral growth-factor complex shows promise for knee and hip:  Clinical trial insights

By: Richard Garian, DC, CCSP; James J. Scaffidi, BS

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Breakthroughs in arthritis – the BMP connection

By: Richard Garian, DC, MS; Arlene Donar, ND; Donald DeFabio, DC; Nancy Gahles, DC; James J. Scaffidi, BS

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Clinical Rounds

Clinical Rounds Overview

Regenerative Tissue Science is proud to present this educational mini-series on stem cell activation with natural bone and cartilage stimulating proteins, reshaping and bridging allopathic and natural medicine.

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Digital Clinical Rounds - Part 1

Bone and Cartilage Stimulating Protein Complex:  Supports de novo Bone and Cartilage Tissue Regeneration via Stem Cell Activation.

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Digital Clinical Rounds – Part 2

Bone and Cartilage Stimulating Protein Complex:  Supports de novo Bone and Cartilage Tissue Regeneration via Stem Cell Activation.

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Core Scientific Research & Reviews

Reduced Expression of BMP-4 and BMP-5 in Arthritis Synovium

“Expression of bone morphogenetic proteins BMP-4 and BMP-5 in synovial tissue from patients with osteoarthritis and rheumatoid arthritis”

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Serum BMPs in Rheumatoid Arthritis (BMP-2, BMP-4, BMP-7)

“Evaluation of serum levels of BMP-2, BMP-4 and BMP-7 in patients with rheumatoid arthritis”

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BMP-9 Promotes Bone Formation in Arthritis Models

“BMP-9 promotes osteogenesis in rheumatoid arthritis synovium via the Smad1/5/8 signaling pathway”

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BMP-7 Intra-articular Injections Improve Cartilage in OA

“Intra-articular administration of bone morphogenetic protein-7 retards progression of cartilage degeneration in rabbit experimental osteoarthritis”

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Dynamic BMP Signaling in Experimental Arthritis

“Dynamic changes in BMP signaling during the development of experimentally induced arthritis”

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BMP-2 Inhibits Pro-Inflammatory Cytokine IL-34 in RA Synoviocytes

“BMP-2 and TGF-β1 down-regulate IL-34 expression in fibroblast-like synoviocytes of patients with rheumatoid arthritis”

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BMP-7 and HO-1 Linked to Bone Markers in RA/AS

“Elevated expression of bone morphogenetic protein 7 (BMP-7) and heme oxygenase-1 (HO-1) in patients with rheumatoid arthritis and ankylosing spondylitis”

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Phase I Trial: BMP-7 in Knee Osteoarthritis

“Safety and tolerability of intra-articular recombinant human bone morphogenetic protein-7 in moderate to severe knee osteoarthritis”

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